2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-16445B
    CNDAC hydrochloride
    		99.59%
    CNDAC hydrochloride is a metabolite of the orally active agent Sapacitabine (HY-16445), and a nucleoside analog. CNDAC hydrochloride induces DNA damage and apoptosis.
    CNDAC hydrochloride
  • HY-100657
    meta-Fexofenadine
    		98.63%
    meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial.
    meta-Fexofenadine
  • HY-135325
    4-Hydroxyacetophenone oxime
    		99.96%
    4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent.
    4-Hydroxyacetophenone oxime
  • HY-118093
    N-benzoyl-L-aspartic acid
    		99.89%
    N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins.
    N-benzoyl-L-aspartic acid
  • HY-B2150
    4-Hydroxyantipyrine
    		99.9%
    4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain.
    4-Hydroxyantipyrine
  • HY-127118
    Pteropterin
    		99.31%
    Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity.
    Pteropterin
  • HY-145991
    Ribavirin carboxylic acid
    		99.85%
    Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity.
    Ribavirin carboxylic acid
  • HY-N6658
    6-Hydroxy-4-methylcoumarin
    		99.30%
    6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity.
    6-Hydroxy-4-methylcoumarin
  • HY-135389
    Desmethyl Levofloxacin
    		99.77%
    Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    Desmethyl Levofloxacin
  • HY-W144096
    Methyl 2,4,6-trihydroxybenzoate
    		98.20%
    Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities.
    Methyl 2,4,6-trihydroxybenzoate
  • HY-B1787
    Sulindac sulfone
    		98.10%
    Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research.
    Sulindac sulfone
  • HY-128696
    Amlodipine aspartic acid impurity
    		99.23%
    Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties.
    Amlodipine aspartic acid impurity
  • HY-100052
    6-Hydroxybentazon
    		99.91%
    6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides.
    6-Hydroxybentazon
  • HY-121208
    Ketanserinol
    		98.05%
    Ketanserinol (R 46742) is a metabolite of Ketanserin (HY-10562). Ketanserinol is a competitive antagonist of the effects of 5-HT (HY-B1473A) in both arteries. The KB values are 6.5 for large coronary arteries and 6.4 for pulmonary arteries.
    Ketanserinol
  • HY-13256A
    Desmethyl Erlotinib
    		98.77%
    Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Desmethyl Erlotinib
  • HY-W019726
    Dehydro Nifedipine
    		99.84%
    Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies.
    Dehydro Nifedipine
  • HY-122440
    Scopoline
    		≥98.0%
    Scopoline (compound 3a) is a compound formed from Scopine (HY-B0459), an α1 adrenergic receptor agonist.
    Scopoline
  • HY-171128
    PTX-M
    		99.95%
    PTX-M is an oxidized metabolite of Pentoxifylline (HY-B0715). Pentoxifylline is a phosphodiesterase inhibitor that can be used for the study of peripheral vascular, inflammatory, and immune diseases.
    PTX-M
  • HY-113121R
    Vanillylmandelic acid (Standard)
    Vanillylmandelic acid (Standard) is the analytical standard of Vanillylmandelic acid. This product is intended for research and analytical applications. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM.
    Vanillylmandelic acid (Standard)
  • HY-135394
    3-Desacetyl Cefotaxime lactone
    3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
    3-Desacetyl Cefotaxime lactone
Cat. No. Product Name / Synonyms Application Reactivity